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Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach

BACKGROUND: Juvenile-onset systemic lupus erythematosus (SLE) is a rare autoimmune rheumatic disease characterised by more severe disease manifestations, earlier damage accrual, and higher mortality than in adult-onset SLE. We aimed to use machine-learning approaches to characterise the immune cell...

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Detalles Bibliográficos
Autores principales: Robinson, George A, Peng, Junjie, Dönnes, Pierre, Coelewij, Leda, Naja, Meena, Radziszewska, Anna, Wincup, Chris, Peckham, Hannah, Isenberg, David A, Ioannou, Yiannis, Pineda-Torra, Ines, Ciurtin, Coziana, Jury, Elizabeth C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425802/
https://www.ncbi.nlm.nih.gov/pubmed/32818204
http://dx.doi.org/10.1016/S2665-9913(20)30168-5