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Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach
BACKGROUND: Juvenile-onset systemic lupus erythematosus (SLE) is a rare autoimmune rheumatic disease characterised by more severe disease manifestations, earlier damage accrual, and higher mortality than in adult-onset SLE. We aimed to use machine-learning approaches to characterise the immune cell...
Autores principales: | Robinson, George A, Peng, Junjie, Dönnes, Pierre, Coelewij, Leda, Naja, Meena, Radziszewska, Anna, Wincup, Chris, Peckham, Hannah, Isenberg, David A, Ioannou, Yiannis, Pineda-Torra, Ines, Ciurtin, Coziana, Jury, Elizabeth C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425802/ https://www.ncbi.nlm.nih.gov/pubmed/32818204 http://dx.doi.org/10.1016/S2665-9913(20)30168-5 |
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