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Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
It remains unknown if biophysical or material properties of biomolecular condensates regulate cancer. Here we show that AKAP95, a nuclear protein that regulates transcription and RNA splicing, plays an important role in tumorigenesis by supporting cancer cell growth and suppressing oncogene-induced...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425812/ https://www.ncbi.nlm.nih.gov/pubmed/32719551 http://dx.doi.org/10.1038/s41556-020-0550-8 |