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Different types of cartilage neotissue fabricated from collagen hydrogels and mesenchymal stromal cells via SOX9, TGFB1 or BMP2 gene transfer

OBJECTIVE: As native cartilage consists of different phenotypical zones, this study aims to fabricate different types of neocartilage constructs from collagen hydrogels and human mesenchymal stromal cells (MSCs) genetically modified to express different chondrogenic factors. DESIGN: Human MSCs deriv...

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Detalles Bibliográficos
Autores principales: Weißenberger, Manuel, Weißenberger, Manuela H., Wagenbrenner, Mike, Heinz, Tizian, Reboredo, Jenny, Holzapfel, Boris M., Rudert, Maximilian, Groll, Jürgen, Evans, Christopher H., Steinert, Andre F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425924/
https://www.ncbi.nlm.nih.gov/pubmed/32790806
http://dx.doi.org/10.1371/journal.pone.0237479