Cargando…

Different types of cartilage neotissue fabricated from collagen hydrogels and mesenchymal stromal cells via SOX9, TGFB1 or BMP2 gene transfer

OBJECTIVE: As native cartilage consists of different phenotypical zones, this study aims to fabricate different types of neocartilage constructs from collagen hydrogels and human mesenchymal stromal cells (MSCs) genetically modified to express different chondrogenic factors. DESIGN: Human MSCs deriv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weißenberger, Manuel, Weißenberger, Manuela H., Wagenbrenner, Mike, Heinz, Tizian, Reboredo, Jenny, Holzapfel, Boris M., Rudert, Maximilian, Groll, Jürgen, Evans, Christopher H., Steinert, Andre F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425924/ https://www.ncbi.nlm.nih.gov/pubmed/32790806 http://dx.doi.org/10.1371/journal.pone.0237479

Ejemplares similares

Combinations of Hydrogels and Mesenchymal Stromal Cells (MSCs) for Cartilage Tissue Engineering—A Review of the Literature
por: Wagenbrenner, Mike, et al.
Publicado: (2021)

Focal cartilage defects of the lateral compartment do influence the outcome after high tibial valgus osteotomy
por: Heinz, Tizian, et al.
Publicado: (2021)

The human arthritic hip joint is a source of mesenchymal stromal cells (MSCs) with extensive multipotent differentiation potential
por: Wagenbrenner, Mike, et al.
Publicado: (2020)

Impact of Tranexamic Acid on Chondrocytes and Osteogenically Differentiated Human Mesenchymal Stromal Cells (hMSCs) In Vitro
por: Wagenbrenner, Mike, et al.
Publicado: (2020)

Is debridement beneficial for focal cartilage defects of the knee: data from the German Cartilage Registry (KnorpelRegister DGOU)
por: Weißenberger, Manuel, et al.
Publicado: (2020)

Epidemiology and Trends in Cartilage Surgery of the Foot and Ankle in Germany: An Analysis of National Healthcare Billing and Reporting Data from 2006 to 2020
por: Eidmann, Annette, et al.
Publicado: (2023)

Correction to: Is debridement beneficial for focal cartilage defects of the knee: data from the German Cartilage Registry (KnorpelRegister DGOU)
por: Weißenberger, Manuel, et al.
Publicado: (2021)

The 3-triangle method preserves the posterior tibial slope during high tibial valgus osteotomy: first preliminary data using a mathematical model
por: Weißenberger, Manuel, et al.
Publicado: (2022)

Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery
por: Weissenberger, M., et al.
Publicado: (2020)

The Direct Anterior Approach (DAA) as a Standard Approach for Total Hip Arthroplasty (THA) in Coxa Profunda and Protrusio Acetabuli? A Radiographic Analysis of 188 Cases
por: Heinz, Tizian, et al.
Publicado: (2023)

Trends in Computer-Assisted Surgery for Total Knee Arthroplasty in Germany: An Analysis Based on the Operative Procedure Classification System between 2010 to 2021
por: Heinz, Tizian, et al.
Publicado: (2023)

No functional differences in anatomic reconstruction with one vs. two suture anchors after non-simultaneous bilateral distal biceps brachii tendon rupture: a case report and review of the literature
por: Weißenberger, Manuel, et al.
Publicado: (2020)

The AMADEUS score is not a sufficient predictor for functional outcome after autologous chondrocyte implantation (ACI) of the knee: data from the German Cartilage Registry (KnorpelRegister DGOU)
por: Heinz, Tizian, et al.
Publicado: (2023)

Can the MRI based AMADEUS score accurately assess pre-surgery chondral defect severity according to the ICRS arthroscopic classification system?
por: Heinz, Tizian, et al.
Publicado: (2022)

Impact of COVID-19 on Fracture Incidence in Germany: A Comparative Age and Gender Analysis of Pre- and Post-Outbreak Periods
por: Heinz, Tizian, et al.
Publicado: (2023)

Regeneration of tracheal neotissue in partially decellularized scaffolds
por: Tan, Zheng Hong, et al.
Publicado: (2023)

The AMADEUS score is not a sufficient predictor for functional outcome after high tibial osteotomy
por: Heinz, Tizian, et al.
Publicado: (2023)

Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy
por: Weißenberger, Manuel, et al.
Publicado: (2023)

Accuracy of Positioning and Risk Factors for Malpositioning Custom-Made Femoral Stems in Total Hip Arthroplasty—A Retrospective Multicenter Analysis
por: Anderson, Philip Mark, et al.
Publicado: (2023)

Total hip arthroplasty in geriatric patients – a single-center experience
por: Anderson, Philip Mark, et al.
Publicado: (2022)

Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers
por: Boelch, Sebastian Philipp, et al.
Publicado: (2018)

The role of vitamin D and vitamin D deficiency in orthopaedics and traumatology—a narrative overview of the literature
por: Maier, Gerrit S., et al.
Publicado: (2021)

Revision Arthroplasty Through the Direct Anterior Approach Using an Asymmetric Acetabular Component
por: Prodinger, Peter Michael, et al.
Publicado: (2020)

Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells
por: Steinert, Andre F, et al.
Publicado: (2012)

Imatinib attenuates neotissue formation during vascular remodeling in an arterial bioresorbable vascular graft
por: Miyachi, Hideki, et al.
Publicado: (2020)

Does vitamin D deficiency predict tumour malignancy in patients with bone tumours? Data from a multi-center cohort analysis
por: Horas, Konstantin, et al.
Publicado: (2020)

Modifiable Individual Risks of Perioperative Blood Transfusions and Acute Postoperative Complications in Total Hip and Knee Arthroplasty
por: Jakuscheit, Axel, et al.
Publicado: (2021)

Custom Made Monoflange Acetabular Components for the Treatment of Paprosky Type III Defects
por: von Hertzberg-Boelch, Sebastian Philipp, et al.
Publicado: (2021)

Collagen‐Based Hydrogels for Cartilage Regeneration
por: Sun, Lihui, et al.
Publicado: (2023)

Bone Metastases of Diverse Primary Origin Frequently Express the VDR (Vitamin D Receptor) and CYP24A1
por: Seiler, Jonas, et al.
Publicado: (2022)

Efficacy of post-operative partial weight-bearing after total knee arthroplasty – a prospective observational trial
por: Anderson, Philip Mark, et al.
Publicado: (2023)

The projected volume of primary and revision total knee arthroplasty will place an immense burden on future health care systems over the next 30 years
por: Klug, Alexander, et al.
Publicado: (2020)

Why compromise the patella? Five-year follow-up results of medial patellofemoral ligament reconstruction with soft tissue patellar fixation
por: Boelch, Sebastian P., et al.
Publicado: (2021)

Diagnosis of Chronic Infection at Total Hip Arthroplasty Revision Is a Question of Definition
por: Boelch, Sebastian Philipp, et al.
Publicado: (2021)

TGFB2-AS1 inhibits triple-negative breast cancer progression via interaction with SMARCA4 and regulating its targets TGFB2 and SOX2
por: Zhou, Cixiang, et al.
Publicado: (2022)

Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue
por: van Haaften, Eline E., et al.
Publicado: (2021)

Case report - calcification of the medial collateral ligament of the knee with simultaneous calcifying tendinitis of the rotator cuff
por: Kamawal, Yama, et al.
Publicado: (2016)

The Wuerzburg procedure: the tensor fasciae latae perforator is a reliable anatomical landmark to clearly identify the Hueter interval when using the minimally-invasive direct anterior approach to the hip joint
por: Rudert, Maximilian, et al.
Publicado: (2016)

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer
por: Armbruster, Nicole, et al.
Publicado: (2017)

Demographics and Trends for Inbound Medical Tourism in Germany for Orthopedic Patients before and during the COVID-19 Pandemic
por: Heinz, Tizian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3uv5u99vb1tu1kb070gscj6uuh