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Exon sequencing mutation detection algorithm based on PCR matching

BACKGROUND: With the development of second-generation sequencing technology, more and more DNA sequence variations have been detected. Exon sequencing is the first choice for sequencing many cancer genes, and it can be better used to identify disease status by detecting gene variants. PCR sequence i...

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Detalles Bibliográficos
Autores principales: Chen, Guobin, Xie, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425927/
https://www.ncbi.nlm.nih.gov/pubmed/32790736
http://dx.doi.org/10.1371/journal.pone.0236709