Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step

Human cytomegalovirus (HCMV) is one of the main causative agents of congenital viral infection in neonates. HCMV infection also causes serious morbidity and mortality among organ transplant patients. Glycoprotein B (gB) is a major target for HCMV neutralizing antibodies, yet the underlying neutraliz...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Xiaohua, Su, Hang, Wrapp, Daniel, Freed, Daniel C., Li, Fengsheng, Yuan, Zihao, Tang, Aimin, Li, Leike, Ku, Zhiqiang, Xiong, Wei, Jaijyan, Dabbu, Zhu, Hua, Wang, Dai, McLellan, Jason S., Zhang, Ningyan, Fu, Tong-Ming, An, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425986/
https://www.ncbi.nlm.nih.gov/pubmed/32745149
http://dx.doi.org/10.1371/journal.ppat.1008736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425986/
https://www.ncbi.nlm.nih.gov/pubmed/32745149
http://dx.doi.org/10.1371/journal.ppat.1008736

Ejemplares similares