Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4(+) T cells post peptide loading

Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an array of immunomodulatory proteins including the B22 family, which has homologs in all patho...

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Detalles Bibliográficos
Autores principales: Forsyth, Katherine S., Roy, Nathan H., Peauroi, Elise, DeHaven, Brian C., Wold, Erik D., Hersperger, Adam R., Burkhardt, Janis K., Eisenlohr, Laurence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425992/
https://www.ncbi.nlm.nih.gov/pubmed/32745153
http://dx.doi.org/10.1371/journal.ppat.1008685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425992/
https://www.ncbi.nlm.nih.gov/pubmed/32745153
http://dx.doi.org/10.1371/journal.ppat.1008685

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