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Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4(+) T cells post peptide loading
Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an array of immunomodulatory proteins including the B22 family, which has homologs in all patho...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425992/ https://www.ncbi.nlm.nih.gov/pubmed/32745153 http://dx.doi.org/10.1371/journal.ppat.1008685 |