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A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats

[Image: see text] Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity and has potentially complex interactions with the gut microbiome. Following untargeted UPLC-qtof-MS an...

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Detalles Bibliográficos
Autores principales: Letertre, Marine P. M., Munjoma, Nyasha, Wolfer, Kate, Pechlivanis, Alexandros, McDonald, Julie A. K., Hardwick, Rhiannon N., Cherrington, Nathan J., Coen, Muireann, Nicholson, Jeremy K., Hoyles, Lesley, Swann, Jonathan R., Wilson, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426014/
https://www.ncbi.nlm.nih.gov/pubmed/32544340
http://dx.doi.org/10.1021/acs.jproteome.0c00230