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A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats
[Image: see text] Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity and has potentially complex interactions with the gut microbiome. Following untargeted UPLC-qtof-MS an...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426014/ https://www.ncbi.nlm.nih.gov/pubmed/32544340 http://dx.doi.org/10.1021/acs.jproteome.0c00230 |