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A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats
[Image: see text] Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity and has potentially complex interactions with the gut microbiome. Following untargeted UPLC-qtof-MS an...
Autores principales: | Letertre, Marine P. M., Munjoma, Nyasha, Wolfer, Kate, Pechlivanis, Alexandros, McDonald, Julie A. K., Hardwick, Rhiannon N., Cherrington, Nathan J., Coen, Muireann, Nicholson, Jeremy K., Hoyles, Lesley, Swann, Jonathan R., Wilson, Ian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426014/ https://www.ncbi.nlm.nih.gov/pubmed/32544340 http://dx.doi.org/10.1021/acs.jproteome.0c00230 |
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