Cargando…

Identification of Genomewide Alternative Splicing Events in Sequential, Isogenic Clinical Isolates of Candida albicans Reveals a Novel Mechanism of Drug Resistance and Tolerance to Cellular Stresses

Alternative splicing (AS)—a process by which a single gene gives rise to different protein isoforms in eukaryotes—has been implicated in many basic cellular processes, but little is known about its role in drug resistance and fungal pathogenesis. The most common human fungal pathogen, Candida albica...

Descripción completa

Detalles Bibliográficos
Autores principales: Muzafar, Suraya, Sharma, Ravi Datta, Shah, Abdul Haseeb, Gaur, Naseem A., Dasgupta, Ujjaini, Chauhan, Neeraj, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426172/
https://www.ncbi.nlm.nih.gov/pubmed/32817456
http://dx.doi.org/10.1128/mSphere.00608-20