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Ybx1 fine-tunes PRC2 activities to control embryonic brain development

Chromatin modifiers affect spatiotemporal gene expression programs that underlie organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial chromatin modifier in executing neurodevelopmental programs. Here, we find that PRC2 interacts with the nucleic acid–binding protein Ybx1. In...

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Detalles Bibliográficos
Autores principales: Evans, Myron K., Matsui, Yurika, Xu, Beisi, Willis, Catherine, Loome, Jennifer, Milburn, Luis, Fan, Yiping, Pagala, Vishwajeeth, Peng, Jamy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426271/
https://www.ncbi.nlm.nih.gov/pubmed/32792512
http://dx.doi.org/10.1038/s41467-020-17878-y