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mTORC1 Is Not Principally Involved in the Induction of Human Endotoxin Tolerance

Endotoxin tolerance represents a safeguard mechanism for preventing detrimental prolonged inflammation and exaggerated immune/inflammatory responses from innate immune cells to recurrent harmless pathogens. On the other hand, excessive immune tolerance can contribute to pathological immunosuppressio...

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Detalles Bibliográficos
Autores principales: Ludwig, Kristin, Husain, Ralf A., Rubio, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426365/
https://www.ncbi.nlm.nih.gov/pubmed/32849516
http://dx.doi.org/10.3389/fimmu.2020.01515