Collagen VIα2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFα signaling

Type VI collagen is well known for its role in muscular disorders, however its function in bone is still not well understood. To examine its role in bone we analyzed femoral and vertebral bone mass by micro-computed tomography analysis, which showed lower bone volume/total volume and trabecular numb...

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Detalles Bibliográficos
Autores principales: Pham, Hai T., Kram, Vardit, Dar, Qurratul-Ain, Komori, Taishi, Ji, Youngmi, Mohassel, Payam, Rooney, Jachinta, Li, Li, Kilts, Tina M., Bonnemann, Carsten, Lamande, Shireen, Young, Marian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426410/
https://www.ncbi.nlm.nih.gov/pubmed/32792616
http://dx.doi.org/10.1038/s41598-020-70730-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426410/
https://www.ncbi.nlm.nih.gov/pubmed/32792616
http://dx.doi.org/10.1038/s41598-020-70730-7

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