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Engineering combinatorial and dynamic decoders using synthetic immediate-early genes
Many cell- and tissue-level functions are coordinated by intracellular signaling pathways that trigger the expression of context-specific target genes. Yet the input–output relationships that link pathways to the genes they activate are incompletely understood. Mapping the pathway-decoding logic of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426417/ https://www.ncbi.nlm.nih.gov/pubmed/32792645 http://dx.doi.org/10.1038/s42003-020-01171-1 |