CRISPR/Cas9 mediated mutation of the mtnr1a melatonin receptor gene causes rod photoreceptor degeneration in developing Xenopus tropicalis

Nighttime surges in melatonin levels activate melatonin receptors, which synchronize cellular activities with the natural light/dark cycle. Melatonin receptors are expressed in several cell types in the retina, including the photon-sensitive rods and cones. Previous studies suggest that long-term ph...

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Detalles Bibliográficos
Autores principales: Wiechmann, Allan F., Martin, Teryn A., Horb, Marko E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426423/
https://www.ncbi.nlm.nih.gov/pubmed/32792587
http://dx.doi.org/10.1038/s41598-020-70735-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426423/
https://www.ncbi.nlm.nih.gov/pubmed/32792587
http://dx.doi.org/10.1038/s41598-020-70735-2

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