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Local and Global Rigidification Upon Antibody Affinity Maturation

During the affinity maturation process the immune system produces antibodies with higher specificity and activity through various rounds of somatic hypermutations in response to an antigen. Elucidating the affinity maturation process is fundamental in understanding immunity and in the development of...

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Detalles Bibliográficos
Autores principales: Fernández-Quintero, Monica L., Loeffler, Johannes R., Bacher, Lisa M., Waibl, Franz, Seidler, Clarissa A., Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426445/
https://www.ncbi.nlm.nih.gov/pubmed/32850970
http://dx.doi.org/10.3389/fmolb.2020.00182