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R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling

Odontoblast cells generated from human dental pulp stem/progenitor cells (hDPSCs) secrete reparative dentin in responds to an injury. Endogenous Wnt signaling is also activated during this process, and these Wnt-activated cells are responsible for the following repair response. R-spondin 2 (Rspo2) i...

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Detalles Bibliográficos
Autores principales: Gong, Yuping, Yuan, Shuai, Sun, Jingjing, Wang, Ying, Liu, Sirui, Guo, Runying, Dong, Wenhang, Li, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426510/
https://www.ncbi.nlm.nih.gov/pubmed/32848860
http://dx.doi.org/10.3389/fphys.2020.00918