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Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy
Both iron metabolism and mitophagy, a selective mitochondrial degradation process via autolysosomal pathway, are fundamental for the cellular well-being. Mitochondria are the major site for iron metabolism, especially the biogenesis of iron-sulfur clusters (ISCs) via the mitochondria-localized ISCs...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426581/ https://www.ncbi.nlm.nih.gov/pubmed/32795936 http://dx.doi.org/10.1016/j.redox.2020.101661 |