Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy

Both iron metabolism and mitophagy, a selective mitochondrial degradation process via autolysosomal pathway, are fundamental for the cellular well-being. Mitochondria are the major site for iron metabolism, especially the biogenesis of iron-sulfur clusters (ISCs) via the mitochondria-localized ISCs...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Wei, Huifang, Zhang, Di, Sehgal, Sheikh Arslan, Zhang, Dejiu, Wang, Xiaohui, Qin, Yan, Liu, Lei, Chen, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426581/
https://www.ncbi.nlm.nih.gov/pubmed/32795936
http://dx.doi.org/10.1016/j.redox.2020.101661

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