Cargando…

Teaching the basics of repurposing mitochondria-targeted drugs: From Parkinson's disease to cancer and back to Parkinson's disease

Parkinson's disease (PD) and cancer share common mutations in mitochondrial proteins: Parkin and PINK1. The overlapping of genes involved in PD and cancer implies that the two diseases might share a common pathogenic mechanism. There are other compelling rationales for a mechanistic link betwee...

Descripción completa

Detalles Bibliográficos
Autor principal: Kalyanaraman, Balaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426584/
https://www.ncbi.nlm.nih.gov/pubmed/32795938
http://dx.doi.org/10.1016/j.redox.2020.101665