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Reparative and toxicity-reducing effects of liposome-encapsulated saikosaponin in mice with liver fibrosis

Saikosaponin d (SSd), a primary active component of the Chinese herb Bupleurum falcatum, has antitumor and antiliver fibrosis effects. However, the toxicity of SSd at high doses can induce conditions such as metabolic disorders and hemolysis in vivo, thus hampering its clinical use. The present stud...

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Detalles Bibliográficos
Autores principales: Shiu, Li-Yen, Huang, Han Hsiang, Chen, Chun Yin, Cheng, Hsia-Ying, Chen, Chih I., Kuo, Shyh Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426636/
https://www.ncbi.nlm.nih.gov/pubmed/32756863
http://dx.doi.org/10.1042/BSR20201219