Transient binding and jumping dynamics of p53 along DNA revealed by sub-millisecond resolved single-molecule fluorescence tracking

Characterization of the target search dynamics of DNA-binding proteins along DNA has been hampered by the time resolution of a standard single-molecule fluorescence microscopy. Here, we achieved the time resolution of 0.5 ms in the fluorescence microscopy measurements by optimizing the fluorescence...

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Detalles Bibliográficos
Autores principales: Subekti, Dwiky Rendra Graha, Murata, Agato, Itoh, Yuji, Takahashi, Satoshi, Kamagata, Kiyoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426816/
https://www.ncbi.nlm.nih.gov/pubmed/32792545
http://dx.doi.org/10.1038/s41598-020-70763-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426816/
https://www.ncbi.nlm.nih.gov/pubmed/32792545
http://dx.doi.org/10.1038/s41598-020-70763-y

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