Cargando…
Engineering designer beta cells with a CRISPR-Cas9 conjugation platform
Genetically fusing protein domains to Cas9 has yielded several transformative technologies; however, the genetic modifications are limited to natural polypeptide chains at the Cas9 termini, which excludes a diverse array of molecules useful for gene editing. Here, we report chemical modifications th...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426819/ https://www.ncbi.nlm.nih.gov/pubmed/32792475 http://dx.doi.org/10.1038/s41467-020-17725-0 |