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Costello syndrome model mice with a Hras(G12S/+) mutation are susceptible to develop house dust mite-induced atopic dermatitis
Costello syndrome is an autosomal dominant disorder that is caused by germline HRAS mutations. Patients with Costello syndrome present craniofacial abnormalities, cardiac defects, and cancer predisposition, as well as skin abnormalities, including papillomas, keratosis pilaris, and eczematous dermat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426869/ https://www.ncbi.nlm.nih.gov/pubmed/32792500 http://dx.doi.org/10.1038/s41419-020-02845-8 |