Costello syndrome model mice with a Hras(G12S/+) mutation are susceptible to develop house dust mite-induced atopic dermatitis

Costello syndrome is an autosomal dominant disorder that is caused by germline HRAS mutations. Patients with Costello syndrome present craniofacial abnormalities, cardiac defects, and cancer predisposition, as well as skin abnormalities, including papillomas, keratosis pilaris, and eczematous dermat...

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Detalles Bibliográficos
Autores principales: Katata, Yu, Inoue, Shin-ichi, Asao, Atsuko, Kobayashi, Shuhei, Terui, Hitoshi, Inoue-Shibui, Aya, Abe, Taiki, Niihori, Tetsuya, Aiba, Setsuya, Ishii, Naoto, Kure, Shigeo, Aoki, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426869/
https://www.ncbi.nlm.nih.gov/pubmed/32792500
http://dx.doi.org/10.1038/s41419-020-02845-8

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