Deletion of DJ-1 in rats affects protein abundance and mitochondrial function at the synapse

DJ-1 is a multifunctional protein affecting different biological and cellular processes. In addition, DJ-1 has roles in regulating mitochondrial function. Loss-of-function mutations in DJ-1 were found to cause an autosomal recessive form of Parkinson’s disease. One of the main pathological features...

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Detalles Bibliográficos
Autores principales: Almikhlafi, Mohannad A., Stauch, Kelly L., Villeneuve, Lance M., Purnell, Phillip R., Lamberty, Benjamin G., Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426919/
https://www.ncbi.nlm.nih.gov/pubmed/32792613
http://dx.doi.org/10.1038/s41598-020-70486-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426919/
https://www.ncbi.nlm.nih.gov/pubmed/32792613
http://dx.doi.org/10.1038/s41598-020-70486-0

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