Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells

Reactive oxygen species (ROS) localized at the precise subcellular compartments are essential for regulating the activity of signaling proteins. Furthermore, ROS are master regulators of tumor malignant progression that respond to a diverse set of environmental stress, especially hypoxia. NADPH oxid...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Wang, Yan, Zhang, Weimin, Zhao, Di, Zhang, Lingyuan, Fan, Jiawen, Li, Jinting, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426961/
https://www.ncbi.nlm.nih.gov/pubmed/32792487
http://dx.doi.org/10.1038/s41392-020-0193-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426961/
https://www.ncbi.nlm.nih.gov/pubmed/32792487
http://dx.doi.org/10.1038/s41392-020-0193-z

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