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Membranous NOX5-derived ROS oxidizes and activates local Src to promote malignancy of tumor cells
Reactive oxygen species (ROS) localized at the precise subcellular compartments are essential for regulating the activity of signaling proteins. Furthermore, ROS are master regulators of tumor malignant progression that respond to a diverse set of environmental stress, especially hypoxia. NADPH oxid...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426961/ https://www.ncbi.nlm.nih.gov/pubmed/32792487 http://dx.doi.org/10.1038/s41392-020-0193-z |