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Administration of small-molecule guanabenz acetate attenuates fatty liver and hyperglycemia associated with obesity

Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive accumulation of hepatic triglycerides (TG) and hyperglycemia arising due to persistent insulin resistance, and is profoundly linked to obesity. However, there is currently no established treatment for NAFLD in obese human subject...

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Detalles Bibliográficos
Autores principales: Yoshino, Satoshi, Iwasaki, Yusaku, Matsumoto, Shunichi, Satoh, Tetsurou, Ozawa, Atsushi, Yamada, Eijiro, Kakizaki, Satoru, Trejo, Juan Alejandro Oliva, Uchiyama, Yasuo, Yamada, Masanobu, Mori, Masatomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426972/
https://www.ncbi.nlm.nih.gov/pubmed/32792584
http://dx.doi.org/10.1038/s41598-020-70689-5