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Administration of small-molecule guanabenz acetate attenuates fatty liver and hyperglycemia associated with obesity
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive accumulation of hepatic triglycerides (TG) and hyperglycemia arising due to persistent insulin resistance, and is profoundly linked to obesity. However, there is currently no established treatment for NAFLD in obese human subject...
Autores principales: | Yoshino, Satoshi, Iwasaki, Yusaku, Matsumoto, Shunichi, Satoh, Tetsurou, Ozawa, Atsushi, Yamada, Eijiro, Kakizaki, Satoru, Trejo, Juan Alejandro Oliva, Uchiyama, Yasuo, Yamada, Masanobu, Mori, Masatomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426972/ https://www.ncbi.nlm.nih.gov/pubmed/32792584 http://dx.doi.org/10.1038/s41598-020-70689-5 |
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