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Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold

Monobodies are synthetic non-immunoglobulin customizable protein binders invaluable to basic and applied research, and of considerable potential as future therapeutics and diagnostic tools. The ability to reversibly control their binding activity to their targets on demand would significantly expand...

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Detalles Bibliográficos
Autores principales: Carrasco-López, César, Zhao, Evan M., Gil, Agnieszka A., Alam, Nathan, Toettcher, Jared E., Avalos, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427095/
https://www.ncbi.nlm.nih.gov/pubmed/32792484
http://dx.doi.org/10.1038/s41467-020-17837-7