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Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma

Chimeric antigen receptor T cells (CAR-T cell) targeting CD19 are effective against several subtypes of CD19-expressing hematologic malignancies. Centralized manufacturing has allowed rapid expansion of this cellular therapy, but it may be associated with treatment delays due to the required logisti...

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Detalles Bibliográficos
Autores principales: Jackson, Zachary, Roe, Anne, Sharma, Ashish Arunkumar, Lopes, Filipa Blasco Tavares Pereira, Talla, Aarthi, Kleinsorge-Block, Sarah, Zamborsky, Kayla, Schiavone, Jennifer, Manjappa, Shivaprasad, Schauner, Robert, Lee, Grace, Liu, Ruifu, Caimi, Paolo F., Xiong, Ying, Krueger, Winfried, Worden, Andrew, Kadan, Mike, Schneider, Dina, Orentas, Rimas, Dropulic, Boro, Sekaly, Rafick-Pierre, de Lima, Marcos, Wald, David N., Reese, Jane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427107/
https://www.ncbi.nlm.nih.gov/pubmed/32849651
http://dx.doi.org/10.3389/fimmu.2020.01941