Andrographolide enhanced radiosensitivity by downregulating glycolysis via the inhibition of the PI3K-Akt-mTOR signaling pathway in HCT116 colorectal cancer cells

OBJECTIVE: Radiotherapy plays an important role in the treatment of colorectal cancer (CRC). However, some patients benefit minimally from radiotherapy because of radioresistance. This study investigated the effects of andrographolide on radiosensitivity in HCT116 CRC cells and examined its mechanis...

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Detalles Bibliográficos
Autores principales: Li, Xiaofei, Tian, Ruifang, Liu, Lan, Wang, Lihui, He, Dong, Cao, Ke, Ma, John K., Huang, Chenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427152/
https://www.ncbi.nlm.nih.gov/pubmed/32787737
http://dx.doi.org/10.1177/0300060520946169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427152/
https://www.ncbi.nlm.nih.gov/pubmed/32787737
http://dx.doi.org/10.1177/0300060520946169

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