Structure of the Inhibited State of the Sec Translocon

Protein secretion in eukaryotes and prokaryotes involves a universally conserved protein translocation channel formed by the Sec61 complex. Unrelated small-molecule natural products and synthetic compounds inhibit Sec61 with differential effects for different substrates or for Sec61 from different o...

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Detalles Bibliográficos
Autores principales: Gérard, Samuel F., Hall, Belinda S., Zaki, Afroditi M., Corfield, Katherine A., Mayerhofer, Peter U., Costa, Catia, Whelligan, Daniel K., Biggin, Philip C., Simmonds, Rachel E., Higgins, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427319/
https://www.ncbi.nlm.nih.gov/pubmed/32692975
http://dx.doi.org/10.1016/j.molcel.2020.06.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427319/
https://www.ncbi.nlm.nih.gov/pubmed/32692975
http://dx.doi.org/10.1016/j.molcel.2020.06.013

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