Paired Helical Filament-Forming Region of Tau (297–391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells

Assembly of tau protein into paired helical filaments and straight filaments is a key feature of Alzheimer's disease. Aggregation of tau has been implicated in neurodegeneration, cellular toxicity and the propagation, which accompanies disease progression. We have reported previously that a reg...

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Detalles Bibliográficos
Autores principales: Pollack, Saskia J., Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E., Al-Hilaly, Youssra K., Rickard, Janet E., Harrington, Charles R., Wischik, Claude M., Serpell, Louise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427330/
https://www.ncbi.nlm.nih.gov/pubmed/32681841
http://dx.doi.org/10.1016/j.jmb.2020.05.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427330/
https://www.ncbi.nlm.nih.gov/pubmed/32681841
http://dx.doi.org/10.1016/j.jmb.2020.05.027

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