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The Axial Alignment of Titin on the Muscle Thick Filament Supports Its Role as a Molecular Ruler
The giant protein titin is expressed in vertebrate striated muscle where it spans half a sarcomere from the Z-disc to the M-band and is essential for muscle organisation, activity and health. The C-terminal portion of titin is closely associated with the thick, myosin-containing filament and exhibit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427331/ https://www.ncbi.nlm.nih.gov/pubmed/32619437 http://dx.doi.org/10.1016/j.jmb.2020.06.025 |