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Inhibiting Heat Shock Protein 90 Protects Nucleus Pulposus-Derived Stem/Progenitor Cells From Compression-Induced Necroptosis and Apoptosis

Nucleus pulposus-derived stem/progenitor cells (NPSCs) provide novel prospects for the regeneration of degenerated intervertebral disc (IVD). Nevertheless, with aging and degeneration of IVD, the frequency of NPSCs markedly decreases. Excessive cell death could be the main reason for declined freque...

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Detalles Bibliográficos
Autores principales: Hu, Binwu, Zhang, Shuo, Liu, Weijian, Wang, Peng, Chen, Songfeng, Lv, Xiao, Shi, Deyao, Ma, Kaige, Wang, Baichuan, Wu, Yongchao, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427414/
https://www.ncbi.nlm.nih.gov/pubmed/32850811
http://dx.doi.org/10.3389/fcell.2020.00685