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Interleukin-27 Functional Duality Balances Leishmania Infectivity and Pathogenesis

IL-27 is a cytokine that exerts diverse effects on the cells of innate and adaptive immune systems. Chiefly expressed in macrophages and dendritic cells during the early phase of Leishmania infection, IL-27 contributes to the protection against L. major infection but suppresses the protective Th1 re...

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Detalles Bibliográficos
Autores principales: Jafarzadeh, Abdollah, Nemati, Maryam, Chauhan, Prashant, Patidar, Ashok, Sarkar, Arup, Sharifi, Iraj, Saha, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427467/
https://www.ncbi.nlm.nih.gov/pubmed/32849534
http://dx.doi.org/10.3389/fimmu.2020.01573