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ATP Signaling Controlling Dyskinesia Through P2X7 Receptors

Dopamine replacement therapy with L-3,4-dihydroxyphenylalanine (L-DOPA) is the only temporary therapy for Parkinson’s disease (PD), but it triggers dyskinesia over time. Since dyskinesia is associated with increased neuronal firing that bolsters purinergic signaling, we now tested whether the select...

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Detalles Bibliográficos
Autores principales: Fonteles, Analu A., Neves, Julliana C. S., Menezes, Ana Paula F., Pereira, Juliana F., Silva, Ana Thais A., Cunha, Rodrigo A., Andrade, Geanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427508/
https://www.ncbi.nlm.nih.gov/pubmed/32848592
http://dx.doi.org/10.3389/fnmol.2020.00111