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Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

BACKGROUND: Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India, the frequency of mutations associated with i...

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Detalles Bibliográficos
Autores principales: Pathak, Ashish, Mårtensson, Andreas, Gawariker, Sudhir, Sharma, Ashish, Diwan, Vishal, Purohit, Manju, Ursing, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427725/
https://www.ncbi.nlm.nih.gov/pubmed/32795288
http://dx.doi.org/10.1186/s12936-020-03274-w