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Transcriptome profiles acquired during cell expansion and licensing validate mesenchymal stromal cell lineage genes

BACKGROUND: Mesenchymal stromal cells (MSCs) are rapidly advancing as commercial therapeutics. However, there are still no adequate tools to validate the identity of MSCs and support standardization of MSC-based products. Currently accepted metrics include cell surface marker profiling and tri-linea...

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Detalles Bibliográficos
Autores principales: Wiese, Danielle M., Braid, Lorena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427746/
https://www.ncbi.nlm.nih.gov/pubmed/32795342
http://dx.doi.org/10.1186/s13287-020-01873-7