Human adiponectin receptor AdipoR1 assumes closed and open structures

The human adiponectin receptors, AdipoR1 and AdipoR2, are key anti-diabetic molecules. We previously reported the crystal structures of human AdipoR1 and AdipoR2, revealing that their seven transmembrane helices form an internal closed cavity (the closed form). In this study, we determined the cryst...

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Detalles Bibliográficos
Autores principales: Tanabe, Hiroaki, Fujii, Yoshifumi, Okada-Iwabu, Miki, Iwabu, Masato, Kano, Kuniyuki, Kawana, Hiroki, Hato, Masakatsu, Nakamura, Yoshihiro, Terada, Takaho, Kimura-Someya, Tomomi, Shirouzu, Mikako, Kawano, Yoshiaki, Yamamoto, Masaki, Aoki, Junken, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427782/
https://www.ncbi.nlm.nih.gov/pubmed/32796916
http://dx.doi.org/10.1038/s42003-020-01160-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427782/
https://www.ncbi.nlm.nih.gov/pubmed/32796916
http://dx.doi.org/10.1038/s42003-020-01160-4

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