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Long-read assays shed new light on the transcriptome complexity of a viral pathogen

Characterization of global transcriptomes using conventional short-read sequencing is challenging due to the insensitivity of these platforms to transcripts isoforms, multigenic RNA molecules, and transcriptional overlaps. Long-read sequencing (LRS) can overcome these limitations by reading full-len...

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Detalles Bibliográficos
Autores principales: Tombácz, Dóra, Prazsák, István, Csabai, Zsolt, Moldován, Norbert, Dénes, Béla, Snyder, Michael, Boldogkői, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427789/
https://www.ncbi.nlm.nih.gov/pubmed/32796917
http://dx.doi.org/10.1038/s41598-020-70794-5