Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists

Pain remains a key therapeutic area with intensive efforts directed toward finding effective and safer analgesics in light of the ongoing opioid crisis. Amongst the neurotransmitter systems involved in pain perception and modulation, the mu-opioid receptor (MOR), a G protein-coupled receptor, repres...

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Detalles Bibliográficos
Autores principales: Kaserer, Teresa, Steinacher, Theresa, Kainhofer, Roman, Erli, Filippo, Sturm, Sonja, Waltenberger, Birgit, Schuster, Daniela, Spetea, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427800/
https://www.ncbi.nlm.nih.gov/pubmed/32796875
http://dx.doi.org/10.1038/s41598-020-70493-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427800/
https://www.ncbi.nlm.nih.gov/pubmed/32796875
http://dx.doi.org/10.1038/s41598-020-70493-1

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