Cargando…

N-acetyl-D-glucosamine kinase binds dynein light chain roadblock 1 and promotes protein aggregate clearance

Emerging evidence indicates that neurodegenerative diseases (NDs) result from a failure to clear toxic protein aggregates rather than from their generation. We previously showed N-acetylglucosamine kinase (NAGK) promotes dynein functionality and suggested this might promote aggregate removal and eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Ripon, Md. Kamal Hossain, Lee, HyunSook, Dash, Raju, Choi, Ho Jin, Oktaviani, Diyah Fatimah, Moon, Il Soo, Haque, Md. Nazmul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427805/
https://www.ncbi.nlm.nih.gov/pubmed/32796833
http://dx.doi.org/10.1038/s41419-020-02862-7