HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway

BACKGROUND: Endothelial injury is one of the predominant pathophysiological characteristics of sepsis and is the major cause of sepsis-induced multiple organ failure. Endothelial pyroptosis is a fatal mechanism of endothelial injury in sepsis, and specific, effective therapies are lacking. Although...

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Detalles Bibliográficos
Autores principales: Peng, Fei, Chang, Wei, Sun, Qin, Xu, Xinyi, Xie, Jianfeng, Qiu, Haibo, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427898/
https://www.ncbi.nlm.nih.gov/pubmed/32795289
http://dx.doi.org/10.1186/s12931-020-01480-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427898/
https://www.ncbi.nlm.nih.gov/pubmed/32795289
http://dx.doi.org/10.1186/s12931-020-01480-3

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