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HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway
BACKGROUND: Endothelial injury is one of the predominant pathophysiological characteristics of sepsis and is the major cause of sepsis-induced multiple organ failure. Endothelial pyroptosis is a fatal mechanism of endothelial injury in sepsis, and specific, effective therapies are lacking. Although...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427898/ https://www.ncbi.nlm.nih.gov/pubmed/32795289 http://dx.doi.org/10.1186/s12931-020-01480-3 |