Two base pair deletion in IL2 receptor γ gene in NOD/SCID mice induces a highly severe immunodeficiency

Genome editing has recently emerged as a powerful tool for generating mutant mice. Small deletions of nucleotides in the target genes are frequently found in CRISPR/Cas9 mediated mutant mice. However, there are very few reports analyzing the phenotypes in small deleted mutant mice generated by CRISP...

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Detalles Bibliográficos
Autores principales: Bak, Inseon, Kim, Doo-Jin, Kim, Hyoung-Chin, Shin, Hye-Jun, Yu, Eunhye, Yoo, Kyeong-Won, Yu, Dae-Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427935/
https://www.ncbi.nlm.nih.gov/pubmed/32817844
http://dx.doi.org/10.1186/s42826-020-00048-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427935/
https://www.ncbi.nlm.nih.gov/pubmed/32817844
http://dx.doi.org/10.1186/s42826-020-00048-y

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